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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UHRF1 All Species: 10.61
Human Site: S666 Identified Species: 23.33
UniProt: Q96T88 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96T88 NP_001041666.1 793 89814 S666 A G S P R R T S K K T K V E P
Chimpanzee Pan troglodytes XP_001139655 792 89650 S665 A G S P R R T S K K T K V E P
Rhesus Macaque Macaca mulatta XP_001082893 795 89906 A668 A V S P R R T A K K S K V E P
Dog Lupus familis XP_868468 799 89797 P672 A G S P G G T P K K S K V E P
Cat Felis silvestris
Mouse Mus musculus Q8VDF2 782 88285 S655 K S T G P T L S S P R A S K K
Rat Rattus norvegicus Q7TPK1 774 87430 T647 K S T G P A T T S P R V S K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507628 851 95788 S724 V D E P K N T S K T M R M A D
Chicken Gallus gallus XP_418269 760 84868 V633 A G A E E K V V S S P A G T P
Frog Xenopus laevis NP_001129236 772 86955 Q645 K R N S D N E Q T A A K S I P
Zebra Danio Brachydanio rerio NP_998242 775 87072 S647 S Q S M E E K S S P T K G T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791602 653 73619 Q527 K G K G K K R Q R E E P Q K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.2 88.1 N.A. 74.9 75.7 N.A. 53.3 71.5 66.5 68 N.A. N.A. N.A. N.A. 47.5
Protein Similarity: 100 99.7 98.8 92.7 N.A. 87 87.5 N.A. 68.5 82 79.9 83 N.A. N.A. N.A. N.A. 62.1
P-Site Identity: 100 100 80 73.3 N.A. 6.6 6.6 N.A. 26.6 20 13.3 33.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 20 26.6 N.A. 46.6 33.3 20 40 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 10 0 0 10 0 10 0 10 10 19 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 10 10 19 10 10 0 0 10 10 0 0 37 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 46 0 28 10 10 0 0 0 0 0 0 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 37 0 10 0 19 19 10 0 46 37 0 55 0 28 19 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % M
% Asn: 0 0 10 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 46 19 0 0 10 0 28 10 10 0 0 73 % P
% Gln: 0 10 0 0 0 0 0 19 0 0 0 0 10 0 0 % Q
% Arg: 0 10 0 0 28 28 10 0 10 0 19 10 0 0 0 % R
% Ser: 10 19 46 10 0 0 0 46 37 10 19 0 28 0 0 % S
% Thr: 0 0 19 0 0 10 55 10 10 10 28 0 0 19 0 % T
% Val: 10 10 0 0 0 0 10 10 0 0 0 10 37 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _